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伊那分室の機器を利用した業績

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2020年度

Tsukagoshi, M., Sirisopapong, M., Namai, F., Ishida, M., Okrathok, S., Shigemori, S., Ogita, T., Sato, T., Khempaka, S., & Shimosato, T. (2020). Lactobacillus ingluviei C37 from chicken inhibits inflammation in LPS-stimulated mouse macrophages. Animal Science Journal, 91(1), 1–7. https://doi.org/10.1111/asj.13436


Shigemori, S., Namai, F., Ogita, T., Sato, T., & Shimosato, T. (2020). Oral priming with oligodeoxynucleotide particles from Lactobacillus rhamnosus GG attenuates symptoms of dextran sodium sulfate-induced acute colitis in mice. Animal Science Journal, 91(1), 6–11. https://doi.org/10.1111/asj.13468


Namai, F., Shigemori, S., Ogita, T., Sato, T., & Shimosato, T. (2020). Construction of genetically modified Lactococcus lactis that produces bioactive anti-interleukin-4 single-chain fragment variable. Molecular Biology Reports, 47(9), 7039–7047. https://doi.org/10.1007/s11033-020-05765-0


Namai, F., Murakami, A., Ueda, A., Tsukagoshi, M., Shigemori, S., Ogita, T., Sato, T., & Shimosato, T. (2020). Construction of Genetically Modified Lactococcus lactis Producing Anti-human-CTLA-4 Single-Chain Fragment Variable. Molecular Biotechnology, 62(11–12), 572–579. https://doi.org/10.1007/s12033-020-00274-8


Namai, F., Shigemori, S., Ogita, T., Sato, T., & Shimosato, T. (2020). Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice. Experimental and Molecular Medicine, 52(9), 1627–1636. https://doi.org/10.1038/s12276-020-00507-5


Mikami, A., Ogita, T., Namai, F., Shigemori, S., Sato, T., & Shimosato, T. (2020). Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue. Molecular Biology Reports, 47(9), 6717–6725. https://doi.org/10.1007/s11033-020-05727-6


Minori Ishida, Fu Namai, Suguru Shigemori, Shoko Kajikawa, Masami Tsukagoshi, Takashi Sato, Tasuku Ogita, Takeshi Shimosatoa (2020). Ribosome-Engineered Lacticaseibacillus rhamnosus Strain GG Exhibits Cell Surface Glyceraldehyde-3-Phosphate Dehydrogenase Accumulation and Enhanced Adhesion to Human Colonic Mucin. Applied and Environmental Microbiology 86(20), 1–10. https://doi.org/10.1128/AEM.01448-20.

 

2022年度

Kimura, N., Saito, K., Niwa, T., Yamakawa, M., Igaue, S., Ohkanda, J., Hosoya T, Kii, I. (2022). Expression and purification of DYRK1A kinase domain in complex with its folding intermediate-selective inhibitor FINDY. Protein Expression and Purification, 195, 106089.

https://doi.org/10.1016/j.pep.2022.106089

2021年度

Miyazaki, Y., Kikuchi M., Umezawa, K., Descamps, A., Nakamura, D., Furuie, G.,  Sumida, T., Saito, K., Kimura, N., Niwa, T., Sumida, Y., Umehara, T., Hosoya, T., & Kii, I. (2021) Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A, European Journal of Medicinal Chemistry, Volume 227, 113948.

https://doi.org/10.1016/j.ejmech.2021.113948

 

Ikeda, T., Watanabe, S., & Mitani, T. (2021). Genistein regulates adipogenesis by blocking the function of adenine nucleotide translocase-2 in the mitochondria. Bioscience, Biotechnology, and Biochemistry, zbab203.  https://doi.org/10.1093/bbb/zbab203

Mitani, T., Tanaka, E., Nakashima, M., Yonemoto, E., Fujii, H., & Ashida, H. (2021). Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner. The Journal of Nutritional Biochemistry, 108898.

https://doi.org/10.1016/j.jnutbio.2021.108898

Irieda, H., & Takano, Y. (2021). Epidermal chloroplasts are defense-related motile organelles equipped with plant immune components. Nature communications, 12:2736. https://doi.org/10.1038/s41467-021-22977-5

Sugimoto, M., Nosho, S., Hikosaka, G., Hattori, Y., Umezawa, K., Kawamura, A., & Makabe, H. (2021). Synthesis of (+)-Muconin via Diastereoselective Oxypalladation. The Journal of organic chemistry, 86(6), 4859-4866.  https://doi.org/10.1021/acs.joc.0c02831

Suzuki, K., Hattori, Y., Kawamura, A., & Makabe, H. (2021). Synthesis of (+)-solenopsin via Pd-catalyzed N-alkylation and cyclization. Bioscience, Biotechnology, and Biochemistry, 85(2), 223-227.  https://doi.org/10.1093/bbb/zbaa014

Nagaoka, Y., Parvatkar, P., Hirai, G., & Ohkanda, J. (2021). Design, synthesis, and functional evaluation of triazine-based bivalent agents that simultaneously target the active site and hot spot of phosphatase Cdc25B. Bioorganic & Medicinal Chemistry Letters, 48, 128265. https://doi.org/10.1016/j.bmcl.2021.128265

 
 
 

2019年度

Tsubamoto, M., Le, T. K., Li, M., Watanabe, T., Matsumi, C., Parvatkar, P., ... & Ohkanda, J. (2019). A Guanidyl‐Based Bivalent Peptidomimetic Inhibits K‐Ras Prenylation and Association with c‐Raf. Chemistry–A European Journal, 25(59), 13531-13536.

Masuda, R., Kawasaki, Y., Igawa, K., Manabe, Y., Fujii, H., Kato, N., ... & Ohkanda, J. (2020). Copper‐Free Huisgen Cycloaddition for the 14‐3‐3‐Templated Synthesis of Fusicoccin‐Peptide Conjugates. Chemistry–An Asian Journal, 15(6), 742-747.

Mitani, T., Watanabe, S., Wada, K., Fujii, H., Nakamura, S., & Katayama, S. (2020). Intracellular cAMP contents regulate NAMPT expression via induction of C/EBPβ in adipocytes. Biochemical and Biophysical Research Communications, 522(3), 770-775.

Miyazawa, Y., Sugimoto, M., Tanaka-Oda, A., & Makabe, H. (2019). Synthesis of (+)-goniopypyrone and (+)-goniotriol using Pd-catalyzed carbonylation. Tetrahedron Letters, 60(36), 151039.

Ogita, T., Yamamoto, Y., Mikami, A., Shigemori, S., Sato, T., & Shimosato, T. (2020). Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice. Frontiers in Immunology, 11, 379.
 

2018年度

Junko Ohkanda, Atsushi Kusumoto, Louvy Punzalan, Ryoma Masuda, Chenyu Wang, Prakash Parvatkar, Dai Akase, Misako Aida, Motonari Uesugi, Yusuke Higuchi and Nobuo Kato: Structural Effects of Fusicoccin upon Upregulation of 14-3-3-Phospholigand Interaction and Cytotoxic Activity. ChemPubSocEurope 24: 16066-16071, 2018.