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Watanabe, S., Haruyama, R., Umezawa, K., Tomioka, I., Nakamura, S., Katayama, S., & Mitani, T. (2023). Genistein enhances NAD+ biosynthesis by upregulating nicotinamide phosphoribosyltransferase in adipocytes. The Journal of Nutritional Biochemistry, 109433.

Yamanaka, K., Inoue, Y., Imanishi, M., & Ohkanda, J. (2023). Functional evaluation of an electrophilic focused library to identify a covalent inhibitor against intrinsically disordered circadian clock transcription factors. Bioorganic & Medicinal Chemistry Letters, 129588.

Kawamura, A., Mizuno, A., Kurakake, M., Yamada, A., & Makabe, H. (2024). Inaoside A: New antioxidant phenolic compound from the edible mushroom Laetiporus cremeiporus. Heliyon, 10(3).

Kameyama, Y., & Makabe, H. (2023). Application of Pd-catalyzed carbonylation followed by spontaneous oxa-Michael addition/diastereoselective reduction of ynone: Synthesis of (+)-goniofufurone. Tetrahedron Letters, 132, 154827.


Kimura, N., Saito, K., Niwa, T., Yamakawa, M., Igaue, S., Ohkanda, J., Hosoya T, Kii, I. (2022). Expression and purification of DYRK1A kinase domain in complex with its folding intermediate-selective inhibitor FINDY. Protein Expression and Purification, 195, 106089.

Tanaka, Y., Kobayashi, S. H., Hattori, Y., Kawamura, A., Makabe, H. (2022). Concise Synthesis of Procyanidin B2 3, 3′′-Digallate Using Yb (OTf) 3-Mediated Self-Condensation. Synlett. 33(11): 1071-1074

Ogino, N., Masuda, R., Punzalan, L. L., Yamashita, E., Igaue, S., Inoue, Y., & Ohkanda, J. (2022). Structure-Activity-Relationship Study of Semi-synthetically Modified Fusicoccins on their Stabilization Effect for 14-3-3-phospholigand Interactions. Bioorganic & Medicinal Chemistry, 117020.


Asami, T., Endo, K., Matsui, R., Sawa, T., Tanaka, Y., Saiki, T., ... & Tanaka, S. (2022). Long-term caloric restriction ameliorates T cell immunosenescence in mice. Mechanisms of Ageing and Development, 206, 111710.


Irieda, H. (2022). Emerging Roles of Motile Epidermal Chloroplasts in Plant Immunity. International Journal of Molecular Sciences, 23(7), 4043.


Endo, K., Sawa, T., Kitamura, H., Umezawa, K., Makabe, H., & Tanaka, S. (2023). Procyanidin B2 3, 3 ″-di-O-gallate suppresses IFN-γ production in murine CD4+ T cells through the regulation of glutamine influx via direct interaction with ASCT2. International Immunopharmacology, 115, 109617.


Tanaka, S. (2023). Modulation of immune function and changes in intestinal flora by Brassica rapa L.(Nozawana). Bioscience, Biotechnology, and Biochemistry,87(5), 465-472.


Miyazaki, Y., Kikuchi M., Umezawa, K., Descamps, A., Nakamura, D., Furuie, G.,  Sumida, T., Saito, K., Kimura, N., Niwa, T., Sumida, Y., Umehara, T., Hosoya, T., & Kii, I. (2021) Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A, European Journal of Medicinal Chemistry, Volume 227, 113948.


Ikeda, T., Watanabe, S., & Mitani, T. (2021). Genistein regulates adipogenesis by blocking the function of adenine nucleotide translocase-2 in the mitochondria. Bioscience, Biotechnology, and Biochemistry, zbab203.

Mitani, T., Tanaka, E., Nakashima, M., Yonemoto, E., Fujii, H., & Ashida, H. (2021). Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner. The Journal of Nutritional Biochemistry, 108898.

Irieda, H., & Takano, Y. (2021). Epidermal chloroplasts are defense-related motile organelles equipped with plant immune components. Nature communications, 12:2736.

Sugimoto, M., Nosho, S., Hikosaka, G., Hattori, Y., Umezawa, K., Kawamura, A., & Makabe, H. (2021). Synthesis of (+)-Muconin via Diastereoselective Oxypalladation. The Journal of organic chemistry, 86(6), 4859-4866.

Suzuki, K., Hattori, Y., Kawamura, A., & Makabe, H. (2021). Synthesis of (+)-solenopsin via Pd-catalyzed N-alkylation and cyclization. Bioscience, Biotechnology, and Biochemistry, 85(2), 223-227.

Nagaoka, Y., Parvatkar, P., Hirai, G., & Ohkanda, J. (2021). Design, synthesis, and functional evaluation of triazine-based bivalent agents that simultaneously target the active site and hot spot of phosphatase Cdc25B. Bioorganic & Medicinal Chemistry Letters, 48, 128265.

Kawahara, T., Ito, A., Kiso, A., Kawamoto, F. (2021). Inhibitory effect of strawberry geranium (Saxifraga stolonifera) on Toll-like receptor 2-mediated inflammatory response in human skin keratinocytes. Journal of Ethnopharmacology 275 (2021) 114039.

Takahashi, F., Endo, K., Matsui, R., Yamamoto, K., Tanaka, S. (2021). Brassica rapa L. activates macrophages via Toll-like receptors. Bioscience, Biotechnology, and Biochemistry, 85(3), 656-665.

Ngyuen, C. T., Ezawa, T., Saito, K. (2022) Polyphosphate polymerizing and depolymerizing activity of VTC4 protein in an arbuscular mycorrhizal fungus. Soil Science and Plant Nutrition. 68(2), 256-267.


Ngyuen, C. T., Saito, K. (2021) Role of cell wall polyphosphates in phosphorus transfer at the arbuscular interface in mycorrhizas. Frontiers in Plant Science. 12, 725939.


Sugiura, Y., Akiyama, R., Tanaka, S., Yano, K., Kameoka, H., Marui, S., Saito, M., Kawaguchi, M., Akiyama, K., Saito, K. (2020) Myristate can be used as a carbon and energy source for the asymbiotic growth of arbuscular mycorrhizal fungi. Proceedings of the National Academy of Sciences of the United States of America. 117(41), 25779-25788.


Kameoka, H., Tsutsui, I., Saito, K., Kikuchi, Y., Handa, Y., Ezawa, T., Hayashi, H., Kawaguchi, M., Akiyama, K. (2019) Stimulation of asymbiotic sporulation in arbuscular mycorrhizal fungi by fatty acids. Nature Microbiology. 4(10), 1654-1660.

Okajima, T., Shigemori, S., Namai, F., Ogita, T., Sato, T. & Shimosato, T. (2021) Free feeding of CpG-oligodeoxynucleotide particles prophylactically attenuates allergic airway inflammation and hyperresponsiveness in mice. Frontiers in Immunology, 12:738041,

Tanaka S, Yamamoto K, Hamajima C, Takahashi F, Endo K, Uyeno Y. Dietary Supplementation with Fermented Brassica rapa L. Stimulates Defecation Accompanying Change in Colonic Bacterial Community Structure. Nutrients. 13(6):1847. 2021.




Tsukagoshi, M., Sirisopapong, M., Namai, F., Ishida, M., Okrathok, S., Shigemori, S., Ogita, T., Sato, T., Khempaka, S., & Shimosato, T. (2020). Lactobacillus ingluviei C37 from chicken inhibits inflammation in LPS-stimulated mouse macrophages. Animal Science Journal, 91(1), 1–7.

Shigemori, S., Namai, F., Ogita, T., Sato, T., & Shimosato, T. (2020). Oral priming with oligodeoxynucleotide particles from Lactobacillus rhamnosus GG attenuates symptoms of dextran sodium sulfate-induced acute colitis in mice. Animal Science Journal, 91(1), 6–11.

Namai, F., Shigemori, S., Ogita, T., Sato, T., & Shimosato, T. (2020). Construction of genetically modified Lactococcus lactis that produces bioactive anti-interleukin-4 single-chain fragment variable. Molecular Biology Reports, 47(9), 7039–7047.

Namai, F., Murakami, A., Ueda, A., Tsukagoshi, M., Shigemori, S., Ogita, T., Sato, T., & Shimosato, T. (2020). Construction of Genetically Modified Lactococcus lactis Producing Anti-human-CTLA-4 Single-Chain Fragment Variable. Molecular Biotechnology, 62(11–12), 572–579.

Namai, F., Shigemori, S., Ogita, T., Sato, T., & Shimosato, T. (2020). Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice. Experimental and Molecular Medicine, 52(9), 1627–1636.

Mikami, A., Ogita, T., Namai, F., Shigemori, S., Sato, T., & Shimosato, T. (2020). Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue. Molecular Biology Reports, 47(9), 6717–6725.

Minori Ishida, Fu Namai, Suguru Shigemori, Shoko Kajikawa, Masami Tsukagoshi, Takashi Sato, Tasuku Ogita, Takeshi Shimosatoa (2020). Ribosome-Engineered Lacticaseibacillus rhamnosus Strain GG Exhibits Cell Surface Glyceraldehyde-3-Phosphate Dehydrogenase Accumulation and Enhanced Adhesion to Human Colonic Mucin. Applied and Environmental Microbiology 86(20), 1–10.


Tsubamoto, M., Le, T. K., Li, M., Watanabe, T., Matsumi, C., Parvatkar, P., ... & Ohkanda, J. (2019). A Guanidyl‐Based Bivalent Peptidomimetic Inhibits K‐Ras Prenylation and Association with c‐Raf. Chemistry–A European Journal, 25(59), 13531-13536.

Masuda, R., Kawasaki, Y., Igawa, K., Manabe, Y., Fujii, H., Kato, N., ... & Ohkanda, J. (2020). Copper‐Free Huisgen Cycloaddition for the 14‐3‐3‐Templated Synthesis of Fusicoccin‐Peptide Conjugates. Chemistry–An Asian Journal, 15(6), 742-747.

Mitani, T., Watanabe, S., Wada, K., Fujii, H., Nakamura, S., & Katayama, S. (2020). Intracellular cAMP contents regulate NAMPT expression via induction of C/EBPβ in adipocytes. Biochemical and Biophysical Research Communications, 522(3), 770-775.

Miyazawa, Y., Sugimoto, M., Tanaka-Oda, A., & Makabe, H. (2019). Synthesis of (+)-goniopypyrone and (+)-goniotriol using Pd-catalyzed carbonylation. Tetrahedron Letters, 60(36), 151039.

Ogita, T., Yamamoto, Y., Mikami, A., Shigemori, S., Sato, T., & Shimosato, T. (2020). Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice. Frontiers in Immunology, 11, 379.



Junko Ohkanda, Atsushi Kusumoto, Louvy Punzalan, Ryoma Masuda, Chenyu Wang, Prakash Parvatkar, Dai Akase, Misako Aida, Motonari Uesugi, Yusuke Higuchi and Nobuo Kato: Structural Effects of Fusicoccin upon Upregulation of 14-3-3-Phospholigand Interaction and Cytotoxic Activity. ChemPubSocEurope 24: 16066-16071, 2018.

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